Thaum Lub Plaub Hlis 15, 2022, kev tsim tawm ntawm Lecardipine hydrochloride lub nplhaib tseem ceeb tau ua tiav ib zaug, thiab tam sim no muaj peev xwm tsim tau yog 5Mt / hli.
Lub npe Askiv:Lercanidipine hydrochloride
Lub npe tshuaj:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-di phenylpropyl)methylamino]-l,l-dimethylethyl methyl ester hydrochloride.
CAS Nr .: 132866-11-6
Daim ntawv thov:Rau kev kho mob ntawm cov tshuaj Lecardipine hydrochloride, nws yuav tsis muaj kev cuam tshuam rau cov ntshav qabzib thiab qib lipid, thiab muaj cov nyhuv antihypertensive.
Market prospect:
Muaj ntau tshaj 200 lab tus neeg mob ntshav siab hauv Suav teb, thiab muaj 10 lab tus neeg mob ntshav siab tshiab txhua xyoo, feem ntau tsis muaj kev tswj hwm, ua rau muaj kev kub ntxhov siab xws li mob stroke, thiab kev tuag txhua xyoo hauv Tuam Tshoj Ntawm 3. lab cov neeg mob uas muaj kab mob plawv, 50% muaj feem cuam tshuam nrog kev kub siab, thiab tus nqi txhua xyoo ntawm kev kho mob plawv yog kwv yees li 309.8 billion yuan.Yog vim li cas rau kev tswj tsis zoo tsis yog tsuas yog cov neeg mob kev paub txog kev kub siab thiab nws cov teeb meem yuav tsum tau txhim kho, tab sis kuj muaj ntau tus neeg mob uas yuav tsum tau noj cov tshuaj tas mus li muaj kev ua tsis zoo thiab tsis tuaj yeem noj tshuaj txhua hnub, txawm li cas los xij, qhov no kuj qhia tau hais tias kev noj tshuaj tsis zoo. antihypertensive tshuaj lag luam muaj peev xwm nthuav.Piv nrog rau cov tshuaj zoo sib xws, locarbodipine hydrochloride muaj zog vascular selectivity.Nws cov cuab yeej lipophilic tshwj xeeb ua rau nws qeeb thiab kav ntev antihypertensive nyhuv Cov nyhuv atherogenic, tshwj xeeb tshaj yog haum rau cov neeg mob ntshav siab nrog atherosclerosis, muaj cov nqi kho mob siab thiab kev lag luam dav dav.
Pharmacological kev txiav txim:
Lecardipine yog ib tiam tshiab ntawm dihydropyridine calcium channel pab pawg neeg hysteresis tus neeg sawv cev, muaj zog vascular selectivity, maj mam, muaj zog antihypertensive nyhuv, ntev ua hauj lwm lub sij hawm, tsis zoo inotropic nyhuv thiab hais txog.Cov kev tshawb fawb hauv vitro tau pom tias locarbodipine muaj qhov cuam tshuam ncaj qha rau ntawm cov leeg nqaij leeg, thiab yog li ntawd muaj cov nyhuv antihypertensive hauv vivo, tab sis muaj kev cuam tshuam me ntsis ntawm lub plawv dhia thiab lub plawv.Vim tias nws cov noob loj hydrophobic thiab muaj zog lipid solubility, locarbodipine tau faib tawm sai sai rau cov ntaub so ntswg thiab cov khoom nruab nrog cev tom qab nkag mus rau hauv lub cev, ua tib zoo khi rau vascular du leeg cell membrane, thiab tso tawm maj mam.Yog li ntawd, txawm hais tias cov ntshav ntawm cov tshuaj no muaj lub sij hawm tshem tawm luv luv ntawm ib nrab-ua tsis tiav, nws cov nyhuv yog ntev-ntev.
Post lub sij hawm: Apr-15-2022